In reply to trollman:
If you have Scarpa feet then your best option is to get a pair of Scarpa 6000's instead of the Spantiks.
Spantiks are narrow(ish) in the forefoot, and if you have wide feet like me, they will put pressure in the area causing discomfort and cold toes, or you'll get them a bit bigger/lace them loosely and then suffer from heel lift and shin rubbing...
FWIW I wear 41 in Scarpas, 41 1/2 in Nepals/Baturas, and 42 in Spantiks. But, and it's a big BUT, if you are heading somewhere cold enough that you need Spantiks, do you want to go with boots you guessed the sizing on by asking strangers in a forum and find out when out in the cold that they don't fit you, are blistering your feet and/or causing you very cold toes?