In reply to kevin stephens:
> First make sure your saddle fore-aft position is right. With feet on the pedals the front of your knee should be directly over the ball of your foot (which should be on, or slightly forward of your pedal). A plumb-line is good for this.
...with your pedal in the foremost position of its rotation, yes?
I was going to suggest the hub thing, but you beat me to it. Seems to be a good general rule of thumb.
Also ensure that your saddle is the right height as this will effect everything; sit on the bike and your heel should just touch the pedal at bottom dead centre when your leg is straight. Again, this is just a rule of thumb but forms a good starting point.
Post edited at 12:13