In reply to jon:
I'm currently in the process of building a board myself. I struggled with the same questions. You can get different grades of OSB, each having various properties but I thought you'd want OSB / 2 at least and ideally OSB / 4? I've used OSB to build an extensive timber out building (15m^2 and 2.5m tall) and it has thus far been generally great. The only issue Ive found is if it get's any significant amount of water in it, then it's rubbish and this stuff is OSB / 4 22m thick! I've also found OSB flexes considerably under load if not supported sufficiently (I used off-cuts to make shelves).
I went for 18mm QMark Plywood from buildbase, which is costly but it should be completely solid. The biggest concern I have with this stuff is it weighs a fair old bit so I might need to beef up the support structure. Either way it'll be solid!
What size timbers are you using for the framing and what separation are you using?