In reply to G. Tiger, Esq.: No, If you consider the use of a quickdraw, one end is in a piece of gear, the other is on the rope.
Now imagine the rope is moved to the side:
If the fixed end is attached to the gear, movement of the rope will pull the sling across, which will cause the karibiner to rotate, potentially moving your gear.
If the loose end is attached to the gear, movement of the rope will still pull the sling across, but it will not (or is less likely to) affect the karibiner attached to the gear, so is safer.
Also one of the karibiners will probably have a bent gate: this is to enable it to clipped to the rope more easily