In reply to Martin1978:
I own a pair of Targhee II Mids.
They are more comfortable straight from the box than any other shoe I've ever owned, save a fully broken in pair of real leather boots.
I wear them true to normal size. I have relatively high arches and a slight pronation, with overall medium width feet (I suppose?!)
They are reliable in anything other than heavy rain - and even then put up a good fight.
There is however, one major caveat:
On one particular type of rock, when wet, the sole offers zero - (and I do mean ZERO!) grip. You quite literally go from walking along in an entirely stable fashion, to ice skating.
Quite frankly it's thoroughly dangerous and I cannot undertsand why they have not resolved the flaw.
Other than this (major?) issue they're great, so I imagine it depends upon what you intend to use them for. The lack of grip has meant that I am uncomortable enough not to use them when I do not know the precise nature of what will be underfoot.