In reply to Dark-Cloud:
I used to use Asics for road running, Salomon for mixed and Innov8 for trail. Salomon and Innov8 seemed OK for me at size 10. Asics have progressively got tighter/smaller over the years so 10 was too small, so I think probably 10.5 for Asics now, however...
I switched to Hoka (for road running) a few months ago after being convinced by a sales guy at a marathon expo and I haven't looked back. I went with size 10.5 (so half a size bigger than my Salomon and Innov8, but probably what I'd go for in an Asics shoe these days) as he suggested going up at least a half size (some go a whole size up he said).
Unlike a previous poster, I did not need to break them in - they were awesome from the start! However, it probably depends which shoes you were used to before you got them.
I'm considering getting the trail version (Challenger?) next as my Salomon's stink and the sole is wearing out. My only concern is whether they are robust enough.