In reply to mypyrex:
I think the times sound reasonable but probably for summer conditions. It says 3 hrs for Thorung Pedi to the pass but for me it was more like 4 hrs in at times waist-deep snow. 4 hrs to descend to Muktinath sounds about right.
In terms of acclimatising i found Nepal much better than the Andes. On the circuit at least you start quite low down and build up height gradually over the next 5-6 days prior to attempt the pass.