In reply to gfpowell: What size are you?
Do you have an idea what sort of foot shape you are? Are you particularly narrow or wide?
Is it a particular part of your foot ankle/heel/ball/toes that didn't suit the Nepals?
About the only useful thing I can say for certain is that Scarpa Jorasses Pro GTX seems to be have marginally larger sizing and a wider fit across the forefoot when compared with Nepals in size 43.