In reply to goldmember:
If they're sleeping 12 hour nights, I hate you
Took our daughter to Australia aged 11 months. First flight to Kuala Lumpur was hard work, as she didn't settle much due to the different environment and noise and, having quite a bit of turbulence on that flight, she had to be on a lap rather than in the basinette. The steward was very tactful when I was walking the aisle with her in suggesting where there was a quiet space at the back of the plane. Subsequent flight to Sydney and rest of the flights that trip were much better.
Since then, the furthest we've gone is Mallorca, but mixed it up by doubling the number of little ones to manage.
Usual long journey tips, take a few favourite toys and books, plenty of snacks and let them burn off energy in the terminal - most seem to have kiddy play areas now. Get them to eat something during take off to help ears pop.
I was once on a long-haul flight a few rows back from a family with 2 kids. No word of a lie, when they got off the plane the area round their seats looked like a bomb had gone off - I've never seen such a mess generated. The cleaners must have had a fit!