In reply to bigbobbyking:
Alps, and specifically a section of one of the long distance paths e.g. E4. The long distance paths are invariably well-served by catered huts or valley hotels and don't seem to go terribly high or over difficult ground. They would seem ideal for your missus. If you want, you can often do higher variations of sections e.g. E4 alpin, or use a cablecar instead of hiking.
SW coastal path - I've a friend currently doing it in sections. She's finding all sorts of issues - closed paths, estuary crossing problems, closed accommodations etc. There is a lot of knowledge out there though, with FB groups and suchlike.
Post edited at 12:35