In reply to Michael Gordon:
well I owned nepal's and I found i needed 46 in them and even then maybe they were a bit small, my street shoe size is normally 44 maybe 45 but never 46. Ofcourse with ice climbing boots its normally best to have a little spare room as kicking steps and front pointing tends to move your feet forward in the boot and stubbing your toes on the end of the boot is no fun at all.
I also found the standard nepal's quite narrow in the toe box. My freneys are much wider here.
One downside to nepal's for some people including myself is the foot bed is very hard and nor very anatomically shaped. If you have high arches this can lead to problems with the ball of the foot.
Post edited at 08:19