In reply to Alasdair Fulton:
This is such a topic and one that is never truly answered often not understood properly, here's what I may or may not have right.
Your screen calibration is an attempt to set the the screen to visually show correct colour representation, so blue looks blue etc.
Print profiling is matching your working colour space to the colour space references to the output method (printer).
So screen calibrating does not mean your print will reflect what you see. If you match your working space with your print profile, you should get prints that match what you see. So if your screen is also calibrated, then the colour spaces are all linked up and wysiwig what you see is what you get.
However this all works in theory, in the last company we spent many £0,000's on getting all our workstations matched to Metro's profile, but in the light booth you could spot differences.