In reply to PPP:
As per other comments, I'd go a half size up for the Mutants.
Only issue I've had is with the laces going, which I've now had on three separate pairs. I've been assured by La Sportiva that this isn't something that they see regularly, but given that it's happened with each pair I own - and also that I'm not doing anything particularly special with the lacing (they're laced how they are out the box) - I'm struggling to find what it is that I'm doing wrong.
The build quality aside from this is excellent. The uppers are sturdy, the sole provides a good balance between grip and durability, and the cushioning seems to take repeated knocks without losing its bounce.