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Helicobacter Pylori

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 tattoo2005 17 Nov 2010
Hiya all, looking for a bit of information if anyone can help.

After months of feeling pretty rubbish with heartburn and abdominal discomfort amongst other unpleasant symptoms I was told by my GP that, after having a blood test done,I had Helicobacter Pylori infection in my tummy and was put on triple therapy with Clarithromycin, Amoxicillin and Proton Pump Inhibitor. I was on this therapy for a week and during that time I felt that my symptoms had vastly improved and could have danced for joy at the relief. This, unfortunately, was short-lived. Two days after finishing the course of treatment my symptoms have returned, nausea, heartburn, the works really and now my GP is sending me for a gastroscopy, she thinks its still the Helicobacter causing the problem but wants to be sure. I wondered if anyone on UKC had been through this sort of thing and can offer any advice, I've kinda started worrying that its all matter of things and am feeling quite anxious about the procedure as well? Any helpful information/support appreciated, thanks. Kirstin X
 DougG 17 Nov 2010
In reply to tattoo2005:

Were you on the triple therapy for long enough, Kirstin?

I suffered for years from those symptoms until a doctor in Aberdeen suggested that I was tested for h.pylori.
I was definitely on the pills for 3 weeks.
(I remember that as I was forbidden to drink any alcohol, and it seemed like a long time!) Did the trick, had no problems since.

Hope you get sorted out - it's no fun.
OP tattoo2005 17 Nov 2010
In reply to DougG: Heya Doug, thanks for the reply, much appreciated. I was only on the therapy for 7 days?? I did look online and it did say 2 weeks in most cases and I just assumed that the GP knew what she was doing?
 DougG 17 Nov 2010
In reply to tattoo2005:

Hmmm. I'm sure the GP knows what she's doing but my doc definitely had me taking them for a lot longer.

Here's a wee story: I was given them just before Xmas (1995 I think it was) and I decided to wait until after the New Year before starting - figured I could put up with a week or two more after suffering all those years. I was in France for Xmas/New Year, and on the way home I was talking to this French bloke at the airport (he subsequently became a good pal), complaining that I wasn't going to be allowed to drink anything at all for 3 weeks. By that he thought I meant no fluids, as opposed to no alcohol. He looked shocked, and said "But you'll die!", to which I said "I know"!!
Removed User 17 Nov 2010
In reply to tattoo2005:
I had Helicobacter in 1996 and it wasn't nice. I went through the triple therapy, and like you the symptoms appeared to return soon after completion. However, my doctor suggested that I continue with a proton pump inhibitor for a couple of months, following the antibiotics and I must tell you that the symptoms gradually eased and then went away completely. The antibiotics continue to work in your systen for a while after you finish the course, so a couple of days may be a little early to assume they've not worked. Hope this is a ray of hope for you. I know how horrible helicobacter is. I wish you the very best in recovering from it.
OP tattoo2005 17 Nov 2010
In reply to DougG: lol! Yeh us Scots WOULD die if we couldnt have alcohol for three weeks lol!! I'm not sure what to do, whether just to keep taking the Omeprazole and wait on my appointment with Consultant at hospital or maybe speak to my GP again and ask if a week is actually enough?? The thought of the gastroscopy is literally making me feel a bit ill but I cant keep feeling this rubbish all the time, the thought of eating anything at the moment makes me nauseated and I seem to be constantly burping, those the nicer symptoms!!!
 Jack Whiteley 17 Nov 2010
In reply to tattoo2005: I would have said 2 weeks is the norm for triple therapy
Removed User 17 Nov 2010
In reply to tattoo2005:
Ps. A gastroscopy is not comfortable, I wasn't, but you can be sedated for it which makes it more bearable I believe. It only takes a couple of minutes and is nothing to worry about really.
 DougG 17 Nov 2010
In reply to tattoo2005:

Not sure what to advise Kirsten, maybe wait and see if anyone else has been through something similar.

I wouldn't fancy the gastroscopy myself but at the same time if it gets rid of the symptoms it'll be worth the unpleasantness.

Very best of luck.
OP tattoo2005 17 Nov 2010
In reply to Removed User: Heya Ally and thanks for the reply AND the wee ray of light at the end of the tunnel, I'm still taking 40mg proton pump inhibitor a day so maybe it will settle down, hopefully before my hospital appointment comes through!! Its just so tiring feeling so rubbish all the time, the relief that I had for that week was an absolute joy!! Did you suffer from distension of your tummy?
OP tattoo2005 17 Nov 2010
In reply to DougG: I'll keep my fingers crossed that it settles down but if not I'm just gonna have to "man up a bit" and get on with the gastroscopy lol! Cheers Doug. X
Removed User 17 Nov 2010
In reply to tattoo2005:
Yes I did, the worst thing about it was that I felt like I had a groaning, gnawing hunger type pain all the time. It wore me out. You will get better, believe me.
OP tattoo2005 17 Nov 2010
In reply to Removed User: I know exactly what you mean ally, I feel hungry but I actually can't face eating sometimes either, sometimes my stomach feels totally full and others completely empty, whether I have eaten or not, its been that bad I've actually gone off eating chocolate for some reason?!
Removed User 17 Nov 2010
In reply to tattoo2005:
What you have to remember is, h.pylori colonizes your stomach wall and will leave a vunerable area once it has been destroyed, this could be the reason why you are still feeling discomfort, the proton pump inhibitor should relieve that to some extent but you must still be careful about what you eat. Best of luck, I feel for you.
OP tattoo2005 17 Nov 2010
In reply to Removed User: I've kind of gone off any sort of greasy foods and chocolate and much prefer to stick to quite plain food at the moment so I'm eating quite a decent diet like chicken, plenty of vegetables and cutting down on sugar as well so fingers crossed that the PPI takes care of the rest and it all settles down again and I can get back to normal, I've even cut down on my red wine intake, I just dont feel like it at the moment and thats not like me at all lol! Thanks very much for your kind words Ally, much appreciated, I'm not feeling quite so panicked now, phew!!!
 climber_medic 17 Nov 2010
In reply to tattoo2005: Hi mate. This might sound like a strange question but have you been under any stress lately?? I had a really bad attack of it 3-4 years ago and now looking back I ca only put it down to the stress of my job. Since leaving in 2008 I have had no such issues
 Dominion 17 Nov 2010
In reply to tattoo2005:

This - http://en.wikipedia.org/wiki/Helicobacter_Pylori#Treatment - says The standard first-line therapy is a one week "triple therapy" consisting of proton pump inhibitors such as omeprazole, lansoprazole and the antibiotics clarithromycin and amoxicillin.[43] Variations of the triple therapy have been developed over the years, such as using a different proton pump inhibitor, as with pantoprazole or rabeprazole, or replacing amoxicillin with metronidazole for people who are allergic to penicillin.

There's some other suggestions as well, maybe not to argue with your GP about but so you have some background knowledge.

||-)
OP tattoo2005 17 Nov 2010
In reply to climber_medic: Heya climber, I've had a wee bit of a stressful time from the beginning of the year but things are hopefully going to start settling down soon since I changed a few things in my life. A stress free life would be ideal, it has been a very busy year for me and I've kinda felt sometimes that I needed just to stop and take a step back but that hasnt been possible at the time.
OP tattoo2005 17 Nov 2010
In reply to Dominion: Heya Dominion, hows you? Thanks for the info, I'll definitely have a read through it, I guess I did the one week therapy but I'm hoping, as ally says, that it will all quieten down with the PPI, fingers crossed. The information is much appreciated, thanks for taking the time to reply, I'm maybe panicking about nothing!!
 abr1966 17 Nov 2010
In reply to tattoo2005: Similar thing symptom wise for me a couple of years ago although the tests came back negative i had the gastroscopy and proton pump inhibitors for probably about 3 months before it was settled properly. Occasionally I still get the symptoms and take the pills for a week or two to settle it....sadly alcohol makes it flare up if i drink too regularly (as in every day for a week or so).

I didn't have any sedation as I knew i'd be picking the kids up from school later in the day. If I had to have one again i'm unsure what i'd decide. Mine took a while as they took a number of biopsies which lengthened the procedur. It was a bit grim to be fair but doesn't last forever so it is a case of getting on with it really, you'd be ok with or without sedation and there are no real after effects.

Best wishes with it, from what I read at the time it sounds like your medication regime has been a bit short lived and taking the proton pump inhibitors may be required for a bit longer yet..
 climber_medic 17 Nov 2010
In reply to tattoo2005: Hi mate. I'm not saying thats the answer but since leaving the Medical world which was very stressful my stomach seems to have settled down alot. I think alot of it was down to not having suitable breaks so we had to get food inside us when we could.

Hope it sorts itself. If not go climbing more it works for me
 IainWhitehouse 17 Nov 2010
In reply to tattoo2005: I was on a proton pump inhibitor for three months or more for what turned out to be stress-related gastritis. Can't offer much help on helicobactor but can tell you the gastroscopy was fine. The very worst I can say of it was that it was very odd. I didn't have sedation and was really glad I didn't. The nurses and doctor/ODP/gastroscoper/whatever-he-was all agreed that the sedation was invariably more unpleasant than the procedure itself.
HTH, Iain
OP tattoo2005 17 Nov 2010
In reply to climber_medic: Heya climber, funnily enough I work in the NHS, maybe a change of job is in order lol! I do eat regularly but I think you may be right in that some of my problem could well be down to stress as well, I'm still on the PPI 40mg so I'll keep taking that and hopefully life should settle down shortly and I might be able to enjoy a glass of red again! I'm still climbing albeit indoors now, its a bit bloody freezing up here in the Highlands and I dont do ice climbing so I'm relegated to the indoor wall, it will keep me going till Spring appears next year!
OP tattoo2005 17 Nov 2010
In reply to abr1966: To be honest abr, I'm terrified of the thought of a gastroscopy, if it was the other end I wouldnt mind so much lol! I've got plenty of Omeprazole to keep me going so have been told to double that up to 40mg a day rather than just 20mg, fingers crossed!! Thank you very much for your reply, much appreciated.
OP tattoo2005 17 Nov 2010
In reply to IainWhitehouse: Hiya Iain, thanks for your reply, as I said earlier I think there is an element of stress, I only moved to Inverness last year and its been a very busy time, new house, new friends, new job etc. Life is quietening down now so hopefully some of the symptoms will too, maybe yoga and massage is the way to go, some relaxation instead of running around daft all the time!
 climber_medic 17 Nov 2010
In reply to tattoo2005: I had one and without making you shitscared i found it bloody awful. Get sedated if they offer it to you as its better than the option i took.

I worked frontline on the ambulances for 5 years with a military medic background also. I guess it all got a bit much in the end so opted to leave.
DaveO@nz 17 Nov 2010
In reply to tattoo2005: A blood test will generally tell you if you have had H Pylori in the past, but not necessarily if it is still active.
There is good evidence that 7 days is sufficient for eradication , but activity of infection should be checked post treatment, as below.
A stool test or a biopsy (performed at gastroscopy) will tell you if you have active H Pylori.
Your symptoms could be due to H Pylori, or stress gastritis or reflux. I'd suggest a Gastroscopy, while unpleasant sounding, is the best way to go for complete diagnosis, reassurance and guiding therapy. I had a similar thing (bronchoscopy) and I was so stoned from the premed it all seemed quite amusing.
OP tattoo2005 17 Nov 2010
In reply to climber_medic: I'll have to be sedated just to get me to the hospital for the procedure and thats no joke! Yeh sometimes you have to take a step back and look after yourself, its hard to admit sometimes that life is difficult or sometimes you just dont realise it, other people see it in you. I hope you are well now though and enjoying the great outdoors, if you are ever up in Scotland pop up to the Highlands, God's own climbing country up here lol!
OP tattoo2005 17 Nov 2010
In reply to DaveO@nz: Yeh Dave, I'm gonna have to "man up a bit" and just get it done, premed sounds good to me as well, I'm not sure I would find it amusing without it
 abr1966 17 Nov 2010
In reply to tattoo2005:
> (In reply to abr1966) To be honest abr, I'm terrified of the thought of a gastroscopy, if it was the other end I wouldnt mind so much lol! I've got plenty of Omeprazole to keep me going so have been told to double that up to 40mg a day rather than just 20mg, fingers crossed!! Thank you very much for your reply, much appreciated.

Bloody hell i'd have the gastro anytime before the camera at the other end! I had to have a cystoscopy once....cameras really aren't made for that..the gastro was much easier than that one!
Maybe there's something about working in the nhs, i do also!
OP tattoo2005 17 Nov 2010
In reply to abr1966: Oh god no, I would have the other end, given the choice lol! Maybe its time for us to get a new job, how's about opening up a climber's B&B somewhere, less stressful perhaps?!?! Can you cook?! lol!
Removed User 17 Nov 2010
In reply to tattoo2005:
Always best to get in for your gastroscopy ahead of the bloke going in for the rectoscopy.
OP tattoo2005 17 Nov 2010
In reply to Removed User: I would hope that working for the NHS I would get preferential treatment.......................but then again maybe not! I'll be first in the queue!!
arctic_hobo 17 Nov 2010
In reply to tattoo2005:

Wondering if you might have a hiatus hernia, which is where the stomach has slightly pushed through the diaphragm causing inflammation of the stomach. Symptoms are almost identical to h.pylori, but obviously it's a different thing to get rid of. I am fairly sure the operation is free, I opted not to have mine as I don't like surgery and it wasn't too bad. It's since improved a lot. It would be very obvious in a gastroscopy so you'll know soon enough.
As for that, I found mine extremely unpleasant (they wedge your mouth open which panicked me and the anaesthetic made me gag uncontrollably) so I'd opt for the sedation, although it means a taxi home and a few extra hours to come out of it OK. PM me if you've questions, these things aren't always nice to chat about on forums.
 Mike Conlon 18 Nov 2010
In reply to tattoo2005: I have an excellent GP who seems to take considerable account of family medical histories. Some years ago he told me he was going to check me out for hp as he had seen some research findings that suggested that there was a link between those with a genetic disposition for bowel cancers (which apparantly I have)and the incidence of hp. Proving positive he advised me to have it erradicated but reasssured me that a very significant proportion of the world's population had hp in their system. He couldn't tell me how I had contracted it nor could he answer my question as to what was to stop me contracting it again. I did'nt have any significant symptoms at the time so wonder if if I might have "recontracted" it since. He agreed when I asked if I should suggest to other family members get checked out for it ! I seem to recall a couple of weeks of antibiotics.
 Dom Whillans 18 Nov 2010
In reply to tattoo2005:
i had a lot of similar symptoms a number of years ago and got tested for HP... tests came back negative and so i was sent for a gastroscopy - I was encouraged to be sedated and it was absolutely fine, that rohypnol stuff really does the business (just get someone to drive you home afterwards). The gastroscopy showed that i have hiatus hernia, (probably from carrying up to 75Kg around building sites as a student) and i have now been on Lansoprazole every day for 5 years! and i get to make people snigger by telling them that i ripped my sphincter hope it pans out fine for you, the procedure isn't bad at all...
 JimS 18 Nov 2010
As said above blood testing for helicoacter shows previous not necessarily current infection. Breath testing or stool testing can indicate current infection status.

In one weeks eradication treatment is normal.

However helicobacter is present in a large proportion of the normal population with out any symptoms. This proportion increases with age.

It is almost always implicated in duodenal ulcers and it has been debated how much importance it has in none ulcer dyspepsia (indigestion). The accepted figure is that you need to treat 15 people with eradication therapy to help one in the long-term in none ulcer dyspepsia. It is probable you felt better during eradication treatment due to the presence of a proton pump inhibitor in the triple therapy regime which hugely reduces acid secretion. Staying on this type of medication either long-term or intermittently will be perfectly reasonable.

The guidance is that gastroscopy the young age group is none productive as the incidence of gastric cancer is vanish in the small.
 Milesy 18 Nov 2010
In reply to tattoo2005:
> Hiya all, looking for a bit of information if anyone can help.
>
> After months of feeling pretty rubbish with heartburn and abdominal discomfort amongst other unpleasant symptoms

At least you have got a potential cause. That's Good

I have suffered Stomach Upset, Stomach Cramps, Gas and Indigestion for years and they have still not found a cause. I have given up hope. It is not HP, it is not a food alergy or intollerance, it is not IBS, it is not excess acid (that is a symptom rather than a cause it seems). It is such a drain when you know your not operating properly and you can not find a reason for it! Best of luck!
 thin bob 18 Nov 2010
In reply to tattoo2005:
hope it all goes well T2

leavening things slightly, I used to work a lot with Campylobacter (what Helicobacter used to be called) and for the life of me, I could never ever type it; it always came out as "Campy lobster". True!
 JimS 18 Nov 2010
campylobacter is still called that and is completley different from helicobacter pylorii
OP tattoo2005 18 Nov 2010
In reply to JimS: Thanks for the info Jim, it seems that I will be on the PPI for the long term according to my GP but if it makes me feel better then I'm happy!!
OP tattoo2005 18 Nov 2010
In reply to Milesy: Yeh I know what you mean Milesy, I've felt rubbish for so long that I have actually forgotten what its like to feel "normal". My GP has mentioned a hiatus hernia as well but we wont know anything until the gastroscopy, noooooooooooooooooooooooooooooooooooo!!!
OP tattoo2005 18 Nov 2010
In reply to Dom Whillans: Heya Dom, yeh my GP has mentioned that it may be a small hernia but will just have to wait and see. I did have a wee snigger at your post, I'm sure it was intended to give me a bit of a laugh so cheers for that! X
Removed User 18 Nov 2010
In reply to tattoo2005: Hiya K! I feel for you. I had a duodenal ulcer and I have a hiatus hernia so I have had the gastroscopy thing twice. I would recommend being sedated as Arctic Hobo suggested. The last time I wasn't sedated and they gave me a local anasthetic which was supposed to taste like banana, I said they should sue the manufacturer, it just tasted gross! The procedure is quite uncomfortable (sorry K!) but it will show what you have and for that reason it is definitely worth it. If you need someone to be there with you or drive you home remember I live on the Black Isle so it would be no trouble at all.
 Fredt 18 Nov 2010
In reply to tattoo2005:

After a couple of years of tests and investigations, I was diagnosed with HP.
All the treatments were undertaken to no avail. I don't know whether I still have HP or not, but I manage the condition my own way. If I follow the rules below I have no problems;

1. No chocolate (the biggest factor)
2. Don't eat after 6pm.
3. Avoid processed food.
4. Dairy products seem to help, especially cheese, but I'm still testing this out.
5. Always keep Rennies handy.

It took a while to adapt to this lifestyle, but I don't suffer anymore.
OP tattoo2005 18 Nov 2010
In reply to Removed User: Heya thanks for that and I will definitely go for the sedation, one of my mates said that she would take me and wait for me but thank you for the kind offer, much appreciated! Hows you anyways, not seen you for about a year!
Removed User 18 Nov 2010
In reply to Fredt: I try to keep to most of those too except chocolate isnt that bad for me. Beer is OK (if its only one glass) but wine and spirits (especially whisky) are right out. Tomatoes are also food of the devil and anything hotter than a korma is a definite no-no.
OP tattoo2005 18 Nov 2010
In reply to Fredt: Hiya Fred, funnily enough I seem to have gone right off chocolate and I'm not sure why, I just find it difficult to face eating it, even white chocolate! I'm sure it wont do me or my teeth any harm to give it up even just for the time being. Not eating after 6pm is quite difficult as I climb after work through the week and am usually dying of starvation afterwards :O(
Removed User 18 Nov 2010
In reply to tattoo2005: Things are so-so. Toby tells me you are down the climbing wall quite a bit so I may see you there. I will liaise with The Tobster!
 sasmojo 18 Nov 2010
In reply to tattoo2005: Hey K.
Tested +ive to this a few years back after 6 months of similar symptoms. I was given amoxicillin for 6 weeks.

I certainly felt a lot better, but was still lacking stamina and strength to get through a normal day, but the other symptoms had cleared up, although I did feel occasionally bloated still.

I decided to see a Nutritional Therapist, to see if a change in diet could help this and a sugar issue I was having. The rest is history. Some of the research that I did and the therapist pointed to suggested that a long term HP infection can change pH in the stomach and that some symptoms may remain if diet goes un-checked.

Still too much rich food can cause me bloating and heartburn, pre HP infection my stomach was steel plated. But the change in diet certainly worked.

That's my experience, take from it what you will.

S
OP tattoo2005 18 Nov 2010
In reply to Removed User: Yeh its back to indoors with the winter setting in, what a joy lol! Catch you down there at some point, take it easy!
OP tattoo2005 18 Nov 2010
In reply to sasmojo: Heya, thanks for the info. My GP did try to refer me to the dietician at the hospital but they wouldnt see me until I had been seen by a Consultant Gastroenterologist, not sure what thats all about?! You would think that they would look at it from a dietary point of view in the first instance but obviously not??
 Chris Craggs Global Crag Moderator 18 Nov 2010
In reply to tattoo2005:
> (In reply to ring ouzel) Heya thanks for that and I will definitely go for the sedation, one of my mates said that she would take me and wait for me but thank you for the kind offer, much appreciated!

They didn't offer me the sedation - I think it is a body-size thing. Not a pleasant experience, though it doesn't last long. When they asked if I wanted to 'have a look' - I wanted to say "Do I bo11***" but its hard to talk with a truncheon down your throat!


Chris
OP tattoo2005 18 Nov 2010
In reply to Chris Craggs: I'll take the sedation even if it means being battered round the head with a frying pan till I pass out lol! I'm not sure I would like to see the inside of my gullet either, I cant imagine it being a very hospitable place!
 Tom G 19 Nov 2010
In reply to tattoo2005:
> (In reply to DougG) Heya Doug, thanks for the reply, much appreciated. I was only on the therapy for 7 days?? I did look online and it did say 2 weeks in most cases and I just assumed that the GP knew what she was doing?

Recommended treatment for triple therapy is ONE week.

This may be followed by 2-3 weeks of antisecretory therapy with acid suppressing drugs.

Source: BNF
 Anni 20 Nov 2010
In reply to tattoo2005:

I had the triple therapy for one week back when I was 18 after testing positive for H Pylori, and continued to have symptoms afterwards. I was in PPI's for around another 2 years before it settled fully, a gastroscopy showed nothing amiss 3 months after the therapy, I was just sore after nearly a year of chucking up most days. (The diagnosis was delayed after the consultant at the time decided I was too young to possibly have ulcers!) Bit annoyed as it was later found that prolonged PPI use increases the risk of stomach cancer, so best to get it all sorted as soon as you can. May well just take a few months to settle, after all if it was ulcers they're pretty nasty :oS

I find porridge is about the only thing that doesn't upset me when I'm having a flare up, thankfully very rare (years apart) now. Really does seem to settle things down. Hope you get it sorted and feel better soon!
 Dax H 20 Nov 2010
In reply to tattoo2005: I was knocking back rennies like no tomorrow so the doc sent me for a gastroscopy ( ok so I can't spell that ). The results were that I had HP.
2 weeks of pills and it went away but the indigestion did not.
For the last 4 years I have taken 1 30mg lanzoprosal every other day and it keeps things in check. If I miss one and go 3 days it takes a few days of 1 per day to get back on track.
OP tattoo2005 21 Nov 2010
In reply to all:

Thanks to everyone for information, advice and support, things have settled down a bit now on 40mg of Omeprazole daily so fingers crossed that everything is getting back on an even keel

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