In reply to Alex Mason: Isn't Creeping Leema E2? The Moon is too conventional to be adventurous, it doesn't stop it being an amazing route. However The Sind or Dogs of War are proper adventure horrorshows for the grade, minimal gear and soft rock.
Some Red Wall route, Infidel might be a contender, as you have to do the first pitch of Pagan. On my personal wishlist. Blue Remembered Hills is pretty adventurous, two cracking pitches one sustained and one with a commiting move to the unknown, however rather too escapable.
Path to Rome would have to figure in the list, awesome traverse for total commitment.
Lubyanka is tough and adventurous for E3 in the mountains.
Manx Wall, is one short pitch, not done it, but looks reasonable for a lleyn route, although often damp, or was after a dry spell when I went down there. Its length prevent it from being most adventurous, as no commitment.
For single pitches some on Doris, but not Cripple Creek as is reasonable after the first 15ft.